Related Experiment Video
Updated: Jun 14, 2025

Author Spotlight: Optimizing Growth Factors for Production of Biotechnologically Relevant Secondary Metabolites
Published on: October 25, 2024
Antioxidants alleviated low-temperature stress in microalgae by modulating reactive oxygen species to improve lipid
Xueting Song1, Fanying Kong2, Bing-Feng Liu1
1State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China.
Abstract:
The aim of this study was to investigate the effects of various concentrations of antioxidants, including butyl hydroxy anisd (BHA), butylated hydroxytoluene (BHT), fulvic acid (FA), melatonin (MT), glycine betaine (GB) and putrescine (Put), on growth and lipid synthesis of microalgae under low-temperature (15 ℃). Changes in biochemical indicators, reactive oxygen species (ROS) level, glutathione (GSH) content and antioxidant enzyme activities were also studied. The results indicated that the maximum biomass concentration (1.3 g/L) and lipid productivity (75.3 ± 5.8 mg/L d-1) were achieved under 100 μM MT and 1 μM GB, respectively. Moreover, antioxidants were able to increase the GSH and antioxidant enzymes activities in algal cells under low-temperature stress. This study was enlightening for the utilization of antioxidants to improve the resistance to low-temperature stress and lipid production in microalgae, and provided a theoretical basis for the application of microalgae for lipid accumulation in cold regions.
Related Concept Videos
Responses to Heat and Cold Stress
Radical Autoxidation
Responses to Salt Stress
Adaptations that Reduce Water Loss

