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Related Concept Videos

Analgesia and Pain Management01:25

Analgesia and Pain Management

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
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Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

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Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
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Local Anesthetics: Adverse Effects01:12

Local Anesthetics: Adverse Effects

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While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
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Nociception01:44

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Nociception—the ability to feel pain—is essential for an organism’s survival and overall well-being. Noxious stimuli such as piercing pain from a sharp object, heat from an open flame, or contact with corrosive chemicals are first detected by sensory receptors, called nociceptors, located on nerve endings. Nociceptors express ion channels that convert noxious stimuli into electrical signals. When these signals reach the brain via sensory neurons, they are perceived as pain.
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Teeth01:15

Teeth

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
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Barriers to Effective Communication II01:21

Barriers to Effective Communication II

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The barriers to effective communication also include cultural barriers, semantic barriers, gender barriers, and time constraints.
Cultural barriers:
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Semantic barriers:
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Meal Duration as a Measure of Orofacial Nociceptive Responses in Rodents
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Systemic Factors Affecting Pain Management in Dentistry.

Davis C Thomas1, Junad Khan2, Sowmya Ananthan3

  • 1Center for Temporomandibular Disorders and Orofacial Pain, Rutgers School of Dental Medicine, 110 Bergen Street, Newark, NJ 07103, USA; Orofacial Pain and Temporomandibular Disorders, Eastman Institute of Oral Health, Rochester, NY 14620, USA.

Dental Clinics of North America
|September 7, 2024
PubMed
Summary

Systemic factors like hormonal imbalances and infections significantly impact dental and orofacial pain. A comprehensive medical history is crucial for effective pain management and reducing healthcare burdens.

Keywords:
Autoimmune and orofacial painDental painHormones and orofacial painInfections and orofacial painNutrition and orofacial painPainSystemic factors

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Area of Science:

  • Oral medicine
  • Systemic health
  • Pain management

Background:

  • Patient pain experience is influenced by local and systemic factors.
  • Systemic factors include hormonal, nutritional, infectious, neurodegenerative, and autoimmune conditions.
  • Understanding these factors is vital for effective pain treatment.

Purpose of the Study:

  • To highlight the importance of systemic factors in dental and orofacial pain.
  • To emphasize the necessity of a comprehensive medical history and review of systems.
  • To improve pain management strategies and patient outcomes.

Main Methods:

  • Review of existing literature on systemic influences on pain.
  • Analysis of how systemic conditions affect dental and orofacial pain perception.
  • Discussion of the role of comprehensive patient evaluation.

Main Results:

  • Systemic factors play a significant role in the experience of dental and orofacial pain.
  • A thorough review of systems is foundational for successful pain prognosis.
  • Early identification of systemic issues can guide appropriate medical referrals.

Conclusions:

  • Comprehensive medical evaluation is essential for managing dental and orofacial pain.
  • Addressing systemic factors can improve pain management and reduce healthcare costs.
  • Interdisciplinary collaboration is key for optimal patient care.