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Published on: May 26, 2023
Association of Previous Cardiac Surgery With Postoperative Pneumonia in Infants Undergoing Abdominal Operations: A
Morgan Zlotolow1, Christian Mpody2, Sergio A Carrillo3
1Department of Pediatrics, Nationwide Children's Hospital and the Ohio State University College of Medicine, Columbus, OH, USA.
Insights
Infants with congenital heart disease (CHD) undergoing abdominal surgery face higher risks of pneumonia and other complications. Close monitoring for respiratory issues post-surgery is crucial for these vulnerable children.
Area of Science:
- Pediatric Surgery
- Cardiology
- Critical Care Medicine
Background:
- Children with congenital heart disease (CHD) often require non-cardiac surgeries.
- These children face increased postoperative complication risks after cardiac repair.
- The study investigates the link between prior cardiac intervention and pneumonia in infants undergoing abdominal surgery.
Purpose of the Study:
- To determine the association between previous cardiac intervention and postoperative pneumonia in infants undergoing abdominal surgery.
- To evaluate the impact of prior cardiac procedures on other adverse surgical outcomes.
Main Methods:
- Retrospective cohort study of 104,820 infants (<12 months) undergoing abdominal surgery (2012-2022).
- Utilized the National Surgical Quality Improvement Program database.
- Employed 1:1 propensity score matching to compare infants with and without previous cardiac interventions.
Main Results:
- 9.3% of infants had prior cardiac interventions.
- Previous cardiac surgery was associated with increased risk of postoperative pneumonia (1.3% vs 0.8%).
- Higher rates of unplanned reintubation, prolonged mechanical ventilation, and extended hospital stays were observed in infants with prior cardiac surgery.
Conclusions:
- Previous cardiac intervention increases the risk of postoperative pneumonia following intra-abdominal surgery.
- These infants are also at higher risk for reintubation, prolonged ventilation, and longer hospital stays.
- Clinicians must vigilantly monitor infants with a history of cardiac intervention for respiratory complications post-surgery.
Background:
Children with congenital heart disease (CHD) often require other, non-cardiac related surgical procedures following their initial cardiac surgery. After full or partial CHD repair, they remain at increased risk of postoperative complications. We examined the association of previous cardiac intervention (surgery or percutaneous catheterization intervention) with postoperative pneumonia in infants undergoing abdominal general surgery.
Methods:
A 1:1 propensity score-matched study was conducted using a retrospective cohort of 104,820 infants (<12 months) who had general abdominal surgeries between 2012 and 2022 in U.S. hospitals participating in the National Surgical Quality Improvement Program. The primary outcome was postoperative pneumonia within 30 days. Secondary outcomes included unplanned reintubation, prolonged mechanical ventilation (>72 h), and extended hospital stay (>75th percentile for the study cohort).
Results:
Of the study cohort, 9736 infants (9.3%) had previous cardiac interventions. In the propensity score-matched sample, infants with previous cardiac surgery had increased risks of postoperative pneumonia (1.3% vs 0.8%; adjusted relative risk [RRadj]: 1.64, 95% CI: 1.22, 2.18, p = 0.001), unplanned reintubation (57.8% vs 32.6%; RRadj: 1.77, 95% CI: 1.77, 1.85, p < 0.001), prolonged mechanical ventilation (5.0% vs 2.3%; RRadj: 2.14, 95% CI: 1.83, 2.52, p < 0.001), and prolonged hospital stays (61.0% vs 53.8%; RRadj: 1.13, 95% CI: 1.10, 1.17, p < 0.001).
Conclusions:
A history of previous cardiac intervention carries an increased risk of postoperative pneumonia, unplanned tracheal reintubation, prolonged mechanical ventilation, as well as longer hospital stays following intra-abdominal surgery. Clinicians should closely monitor these patients for respiratory complications after surgery.
Level Of Evidence:
II.
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