Related Experiment Video
Updated: Jun 14, 2025

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
Hyperaldosteronism secondary to renal agenesis: An unusual cause for hypertension in pregnancy
Nalini Newbigging1, Sowmya Sathyendra2, Sudha Jasmine2
1Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
Abstract:
Literature with regards to pregnancy related outcomes in persons with the presence of a solitary kidney of any cause is scarce. Most of the available information has been extrapolated from persons who have been renal donors. Unilateral renal agenesis affects 1 in 1500 people and can present with resistant hypertension. When a woman with a solitary kidney presents in pregnancy, it may be both a challenging diagnostic and therapeutic problem. Eplerenone, a selective aldosterone blocker has been prescribed for resistant hypertension and in the presence of pregnancy, been useful in persons with primary hyperaldosteronism and resistant hypertension due to obstructive sleep apnoea. We describe the use of Eplerenone in a patient with resistant hypertension in pregnancy, due to secondary hyperaldosteronism precipitated by renal agenesis.
Related Concept Videos
Hormonal Regulation
Antihypertensive Drugs: Potassium-Sparing Diuretics
Adrenal Gland Disorders
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Antihypertensive Drugs: Direct Renin Inhibitors
Hypertension and Regulation of Blood Pressure
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors

