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Teeth

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...

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Updated: Jun 13, 2025

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model

Published on: January 13, 2023

Third Molar Extractions in Patients With Developmental Disabilities.

Michael C Britt¹, Elise A Sepe¹, Mark A Green²

¹Clinical Research Assistant, Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, MA.

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons

|September 8, 2024

Summary

This summary is machine-generated.

Patients with developmental disabilities undergoing third molar extractions do not face a higher risk of surgical site infections. This study found no significant difference in infection rates between groups, suggesting comparable safety outcomes.

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Area of Science:

Oral and Maxillofacial Surgery
Dental Public Health
Developmental Disabilities Research

Background:

Patients with developmental disabilities may have unique challenges impacting oral hygiene and post-surgical recovery.
Third molar extractions carry a risk of surgical site infections (SSIs), necessitating an understanding of risk factors.

Purpose of the Study:

To compare the incidence of SSIs after third molar removal in patients with and without developmental disabilities.
To identify potential disparities in surgical outcomes based on developmental disability status.

Main Methods:

Retrospective cohort study at Boston Children's Hospital (2021-2023).
Included patients undergoing extraction of all four third molars.
Compared SSI rates between patients with and without developmental disabilities, controlling for covariates like age, sex, and anesthesia type.

Main Results:

1,896 subjects evaluated; 236 with developmental disabilities.
Overall SSI rate was 2.7%.
No statistically significant difference in SSI rates between the developmental disability group (0.8%) and the non-developmental disability group (3.0%), P=0.057.

Conclusions:

Developmental disability status is not associated with an increased risk of postoperative surgical site infections after third molar extractions.
Findings suggest that patients with developmental disabilities can undergo third molar surgery with comparable safety to the general population.