May-Thurner Syndrome: A Rare, Yet Recognized, Cause of Deep Vein Thrombosis

Zaid Al Ghananeem1, Amit Deshpande2, Vaibhav Sundaresan1

  • 1Vascular Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, GBR.

Cureus
|September 9, 2024
PubMed

Insights

May-Thurner syndrome (MTS), a rare condition causing left leg deep vein thrombosis (DVT), was successfully treated in a young patient with thrombus removal and stenting. This intervention resolved DVT and pulmonary embolism symptoms.

Area of Science:

  • Vascular Surgery
  • Cardiology
  • Radiology

Background:

  • May-Thurner syndrome (MTS) is a vascular condition characterized by the compression of the left common iliac vein (CIV) by the right common iliac artery (CIA).
  • This chronic compression can lead to venous stasis and increase the risk of deep vein thrombosis (DVT) in the left lower extremity.
  • MTS is often underdiagnosed, particularly in younger individuals presenting with seemingly idiopathic DVT.

Observation:

  • A 19-year-old patient presented with severe left-sided DVT, including significant thigh pain, erythema, and ambulation difficulties.
  • The patient also experienced pleuritic chest pain, indicative of a pulmonary embolism (PE).
  • Diagnostic imaging confirmed severe MTS as the underlying cause of the DVT and subsequent PE.

Findings:

  • The patient underwent successful surgical thrombectomy to remove the thrombus from the left CIV.
  • Endovascular stenting of the narrowed left CIV was performed to restore venous outflow.
  • Post-procedural assessment showed resolution of DVT symptoms and successful management of PE.

Implications:

  • This case highlights the importance of considering MTS in young patients with left lower extremity DVT and PE.
  • Timely diagnosis and intervention, including surgical and endovascular techniques, can lead to favorable outcomes in severe MTS.
  • Effective management of MTS can prevent long-term complications associated with chronic venous obstruction and recurrent thromboembolic events.

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