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Updated: Jun 13, 2025

Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
Published on: September 20, 2021
Mysterious Keratitis Responding Favorably to Antiviral Therapy
Surbhi A Chodvadiya1, Megha R Kotecha1, Varsha Manade1
1Department of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pune, IND.
Abstract:
Keratitis, characterized by inflammation of the cornea, presents a diagnostic challenge, particularly when the etiology remains elusive. Here, we report a perplexing case of keratitis in a 35-year-old patient with no identifiable risk factors or predisposing conditions. Despite the initial uncertainty, empirical treatment with antiviral medications led to a rapid resolution of symptoms and improvement in corneal health. This case underscores the importance of considering viral etiologies even in cases with atypical presentations and highlights the potential efficacy of antiviral therapy in such scenarios. Further investigation is needed to understand the underlying causes and improve treatment approaches for similar cases of unexplained keratitis.
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