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Case Report: Exacerbation after fat grafting in patients with active localized scleroderma
Shunxin Han1, Juzi Liu1, Feng Lu1
1Department of Plastic and Reconstructive Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Frontiers in Surgery
|September 9, 2024
Summary
Autologous fat grafting may worsen active localized scleroderma (LoS). This case study highlights potential risks, suggesting caution when performing cosmetic procedures during active LoS phases.
Area of Science:
- Dermatology
- Plastic Surgery
- Regenerative Medicine
Background:
- Autologous fat transplantation is increasingly used for facial lesions.
- Localized scleroderma (LoS) is a chronic autoimmune condition affecting the skin.
- Previous reports suggest fat grafting may be beneficial for LoS-related facial atrophy.

