Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

396
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
396
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

474
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
474
Immunological Memory01:23

Immunological Memory

560
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
560
Special Features of Adaptive Immunity01:20

Special Features of Adaptive Immunity

776
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
776
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

923
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
923
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

26
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
26

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The past, present, and future of anti-idiotype antibodies.

Frontiers in immunology·2025
Same author

Extensive Gaseous Emissions Reduction of Firewood-Fueled Low Power Fireplaces by a Gas Sensor Based Advanced Combustion Airflow Control System and Catalytic Post-Oxidation.

Sensors (Basel, Switzerland)·2023
Same author

Application of a Robust Thermoelectric Gas Sensor in Firewood Combustion Exhausts.

Sensors (Basel, Switzerland)·2023
Same author

What Can We Learn from Research with Monoclonal Antibody 1F7?

Monoclonal antibodies in immunodiagnosis and immunotherapy·2022
Same author

Expert Panel Discussion on Antigenic Sin.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2021
Same author

The Impact of the Hybridoma Technology on the R&D of Idiotypic Antibodies.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2021
Same journal

A Novel Anti-Glypican-3 Monoclonal Antibody G<sub>3</sub>Mab-25 for Versatile Applications.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Epitope Mapping of Anti-mouse ACKR4 Monoclonal Antibodies Developed by N-Terminal Peptide Immunization.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Epitope Mapping of Anti-Mouse C-C Motif Chemokine Receptor 1 Monoclonal Antibodies Developed by the Cell-Based Immunization and Screening Method.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Guidelines for Reporting New Monoclonal Antibodies: Improving Transparency, Reproducibility, and Research Utility.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Establishment of a Novel Anti-EphA4 Monoclonal Antibody, Ea<sub>4</sub>Mab-3, for Versatile Applications.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
Same journal

Acknowledgment of Reviewers 2025.

Monoclonal antibodies in immunodiagnosis and immunotherapy·2026
See all related articles

Related Experiment Video

Updated: Jun 13, 2025

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

3.5K

Immune Jumping in Autoimmune Long-Covid.

Heinz Kohler1

  • 1Department of Microbiology and Immunology, University of Kentucky, Lexington, Kentucky, USA.

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
|September 9, 2024
PubMed
Summary
This summary is machine-generated.

Long-Covid, a multi-system illness, presents diverse symptoms making its cause unclear. This study proposes autoimmune reactions, where the anti-SARS-CoV response targets the body, as a potential cause for Long-Covid disease.

Keywords:
Covid-19Long-Covidantiidiotypeidiotypyimmune networkimmune responseregulation

More Related Videos

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
09:38

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

Published on: September 12, 2016

12.2K
Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

781

Related Experiment Videos

Last Updated: Jun 13, 2025

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

3.5K
Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
09:38

Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

Published on: September 12, 2016

12.2K
Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research
05:55

Author Spotlight: Novel Assay for Studying B-Cell Responses in Multiple Sclerosis Research

Published on: December 1, 2023

781

Area of Science:

  • Immunology
  • Infectious Diseases
  • Pathology

Background:

  • Long-Covid exhibits a wide range of multi-organ symptoms, from fatigue to clotting issues and autoantibodies.
  • The diverse clinical presentation complicates identifying a single immunopathogenic cause for Long-Covid.

Purpose of the Study:

  • To evaluate different immune pathways implicated in Long-Covid.
  • To propose a unifying hypothesis for the immunopathogenesis of Long-Covid disease.

Main Methods:

  • Critical evaluation of various immune response pathways in Long-Covid.
  • Analysis of the immune network to understand the redirection of anti-SARS-CoV responses.

Main Results:

  • The study suggests that autoimmune reactions may be the primary cause of Long-Covid.
  • Evidence indicates a shift in the immune response, targeting self-antigens instead of SARS-CoV-2.

Conclusions:

  • Autoimmune reactions, driven by a misdirected immune response, are hypothesized as the cause of Long-Covid.
  • Therapeutic strategies targeting the autoimmune pathway are proposed for Long-Covid treatment.