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Comparative efficacy of pharmacological and non-pharmacological interventions for mitigating pain and anxiety

Sherzad Khudeida Suleman1, Nizer Yahya2, Stefan Nilsson3

  • 1Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden sherzadkhudeida@uod.ac.

BMJ Paediatrics Open
|September 9, 2024
PubMed

Insights

A combination of topical analgesic cream (TKTX cream) and a distraction technique (Trace Image and Colouring for Kids-Book, TICK-B) significantly reduced pain and fear in children during venipuncture. This combined approach offers a practical strategy for managing needle-related distress in pediatric patients.

Area of Science:

  • Pediatric Medicine
  • Pain Management
  • Medical Procedures

Background:

  • Venipuncture is a common yet painful procedure for children.
  • Effective pain and fear management is crucial for pediatric patient experience.
  • This study evaluated a combined intervention for venipuncture-related distress.

Purpose of the Study:

  • To assess the efficacy of TKTX cream and TICK-B distraction in reducing pediatric venipuncture pain and fear.
  • To compare the combined approach against individual interventions and a control group.

Main Methods:

  • A randomized controlled trial involving 176 children aged 6-12 years.
  • Participants were assigned to TICK-B, TKTX cream, combined TICK-B+TKTX cream, or control groups.
  • Pain and fear were measured using validated scales post-venipuncture.

Main Results:

  • The combined TICK-B and TKTX cream intervention significantly reduced pain intensity (2.80 vs 7.24) and fear levels (0.93 vs 2.83) compared to controls (p<0.001).
  • This combination was more effective than individual interventions in alleviating procedural pain and anxiety.

Conclusions:

  • Combined use of TICK-B distraction and TKTX cream is highly effective for managing pediatric venipuncture pain and fear.
  • This strategy provides a practical solution for healthcare providers to improve needle procedure management in children.
Abstract

Keywords:
AnesthesiaHealth services researchPainPharmacology

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