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Updated: May 6, 2026

A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
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Potential drug targets for osteoporosis identified: A Mendelian randomization study

Guolong Zhao1, Qian Wang1, Ning Duan1

  • 1Department of Orthopaedics, Honghui Hospital, Xi'an Jiaotong University, 555 Youyi East Road, Xi'an, 710054, Shaan'xi Province, China.

Heliyon
|September 10, 2024
PubMed
Summary

This study identified six druggable genes, including IL32 and ST6GAL1, as potential targets for osteoporosis treatment. Further clinical research is recommended to explore these novel osteoporosis drug targets.

Keywords:
DrugMendelian randomizationOsteoporosisRisk factorSingle-cell expression

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