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Switch from methadone to buprenorphine with microinduction in outpatient setting

Farid Juya1, John Fredrik Askjer1, Linda Merete Kaaberg Dahl1

  • 1Klinikk psykisk helse og avhengighet, Sykehuset i Vestfold, Tønsberg.

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|September 10, 2024
PubMed
Abstract

Insights

Switching from methadone to buprenorphine can be done gently in an outpatient setting. This microinduction approach avoids opioid withdrawal symptoms, offering a patient-friendly alternative for opioid maintenance therapy.

Area of Science:

  • Addiction Medicine
  • Pharmacology

Background:

  • Opioid maintenance therapy (OMT) often involves methadone.
  • Switching from methadone to buprenorphine can be challenging, typically requiring inpatient care and causing withdrawal.
  • Current methods often necessitate an opioid-free day, leading to discomfort.

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