A grain-like cerium oxide nanostructure: synthesis and uric acid sensing application

Area of Science:

• Nanomaterials Science
• Electrochemistry
• Sensor Technology

Background:

• Nanomaterials enhance sensor sensitivity for analyte detection.
• Cerium oxide (CeO2) nanostructures offer unique properties for electrochemical applications.

Purpose of the Study:

• To synthesize and characterize grain-like CeO2 nanostructures.
• To fabricate and evaluate a CeO2-modified screen-printed carbon electrode (SPCE) sensor for uric acid (UA) detection.

Main Methods:

• Facile synthesis of grain-like CeO2 nanostructures.
• Drop-casting of CeO2 slurry onto SPCE to create the sensor.
• Electrochemical characterization and CV-based sensing of UA.

Main Results:

• Synthesized CeO2 exhibited grain-like morphology, good crystallinity, and excellent vibrational properties.
• The CeO2-modified SPCE showed enhanced charge-transfer behavior compared to bare SPCE.
• The sensor demonstrated linear performance for UA detection up to 1070 μM with high sensitivity, low detection limit, reproducibility, selectivity, and stability.

Conclusions:

• The CeO2-modified SPCE sensor is a promising device for sensitive and selective UA detection.
• The developed sensor addresses the need for timely UA concentration monitoring in real samples.