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Updated: Jun 13, 2025

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants
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Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

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The association between prenatal pyrethroids exposure and children's health - current research

Agnieszka Jankowska1, Maja Ścieszko1,2, Alicja Polańska3

  • 1Nofer Institute of Occupational Medicine, Łódź, Poland (Department of Environmental and Occupational Health Hazards).

International Journal of Occupational Medicine and Environmental Health
|September 10, 2024
PubMed

Insights

Prenatal exposure to pyrethroids, common insecticides, shows uncertain health effects in children. Research indicates potential neurobehavioural impacts, but more studies are needed to confirm risks.

Area of Science:

  • Environmental Health
  • Pediatric Health
  • Toxicology

Background:

  • Pyrethroids are widely used insecticides in agriculture, forestry, and homes.
  • Exposure to pyrethroids is a significant public health concern, particularly regarding potential effects on children's health.
  • Prenatal exposure is a critical window for potential adverse health outcomes.

Purpose of the Study:

  • To systematically review and summarize current knowledge on the health effects of prenatal pyrethroid exposure in children.
  • To assess impacts on pregnancy course and outcome, child health status, and neurobehavioural development.
  • To identify gaps in research and areas for future investigation.

Main Methods:

  • A systematic literature search was conducted in PubMed, Web of Science, and Scopus databases (January-February 2024).
  • Included original, peer-reviewed English-language articles published since 2015.
  • Screened 198 studies, ultimately analyzing 25 relevant articles.

Main Results:

  • The review analyzed studies on neurobehavioural development (16 articles), pregnancy outcomes (3 articles), respiratory disease (3 articles), obesity (1 article), and growth/body composition (2 articles).
  • Considerable uncertainty exists regarding the adverse effects of prenatal pyrethroid exposure on children's health.
  • The strongest, though inconsistent, evidence points to potential impacts on neurobehavioural development.

Conclusions:

  • Current evidence on the adverse health effects of prenatal pyrethroid exposure in children is limited and often inconsistent.
  • Further research is essential to elucidate the mechanisms of action and confirm health effects in vulnerable populations.
  • Understanding pyrethroid toxicity is crucial for public health protection, especially for pregnant women and children.

Keywords:
fetal growthneurobehavioural developmentobesityprenatal exposurepyrethroidsrespiratory diseases

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