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Updated: Jun 13, 2025

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Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions
Published on: June 21, 2024
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The Intrauterine Device: How to Deploy This Strategy in the Molecular World?
Paul Johannet1, Claire F Friedman1,2
1Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Abstract:
Progestin-based therapy can safely be offered to a subset of patients with atypical endometrial hyperplasia or grade 1 endometrioid endometrial cancer who desire fertility preservation. A recent study shows that levonorgestrel intrauterine device confers durable clinical benefit and identifies possible immune mechanisms of relapse and resistance. See related article by Bowen et al., p. 5073.

