Drug-induced lysosomal lipidosis: biochemical interpretations

LY207320 (6-methylene-4-pregnene-3,20-dione) inhibits testosterone biosynthesis, androgen uptake, 5 alpha-reductase, and produces prostatic regression in male rats.

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17 beta-(cyclopropylamino)-androst-5-en-3 beta-ol, a selective mechanism-based inhibitor of cytochrome P450(17 alpha) (steroid 17 alpha-hydroxylase/C17-20 lyase).

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A normal phase high-performance liquid chromatography system for steroid 17 alpha-hydroxylase/C17-20 lyase (cytochrome P-450 21scc) assays.

Analytical biochemistry·1988

Pharmacological induction of 5 alpha-reductase deficiency in the rat: separation of testosterone-mediated and 5 alpha-dihydrotestosterone-mediated effects.

Endocrinology·1986

Preparation of 20-(hydroxymethyl)-4-methyl-4-aza-2-oxa-5 alpha-pregnan-3-one as an inhibitor of testosterone 5 alpha-reductase.

Journal of medicinal chemistry·1985

Toxicity and teratogenicity studies with the hypolipidemic drug RMI 14,514 in rats.

Fundamental and applied toxicology : official journal of the Society of Toxicology·1981

Peptide hormone-based combinational pharmacotherapies for chronic metabolic diseases.

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Self-collected dried blood spots for phosphatidylethanol assessment in virtual trials: Feasibility and concordance with self-reported alcohol use among men at high HIV risk.

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Early-life gut dysbiosis programs divergent metabolic trajectories in a sex-dependent manner.

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Drug-induced lysosomal lipidosis: biochemical interpretations

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LY207320 (6-methylene-4-pregnene-3,20-dione) inhibits testosterone biosynthesis, androgen uptake, 5 alpha-reductase, and produces prostatic regression in male rats.

17 beta-(cyclopropylamino)-androst-5-en-3 beta-ol, a selective mechanism-based inhibitor of cytochrome P450(17 alpha) (steroid 17 alpha-hydroxylase/C17-20 lyase).

A normal phase high-performance liquid chromatography system for steroid 17 alpha-hydroxylase/C17-20 lyase (cytochrome P-450 21scc) assays.

Pharmacological induction of 5 alpha-reductase deficiency in the rat: separation of testosterone-mediated and 5 alpha-dihydrotestosterone-mediated effects.

Preparation of 20-(hydroxymethyl)-4-methyl-4-aza-2-oxa-5 alpha-pregnan-3-one as an inhibitor of testosterone 5 alpha-reductase.

Toxicity and teratogenicity studies with the hypolipidemic drug RMI 14,514 in rats.

Peptide hormone-based combinational pharmacotherapies for chronic metabolic diseases.

Chronic pain in Alzheimer disease and the role of neuroimmune interactions.

Renal aging and associated diseases: Common mechanisms and therapeutic approaches.

Recent advances in methotrexate pharmacology and potential therapeutic uses in age-related cardiometabolic and neurodegenerative diseases.

Exploration of multifunctional characteristics and regulatory mechanism of promoter G-quadruplexes.

Aryl hydrocarbon receptor pharmacology-mechanisms, ligands, and therapeutic potential.

Integrated non-targeted and targeted metabolomics reveals tryptophan metabolism disorders in hypertension.

Self-collected dried blood spots for phosphatidylethanol assessment in virtual trials: Feasibility and concordance with self-reported alcohol use among men at high HIV risk.

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Coconut Haustorium Alleviates Fructose-Induced Redox Imbalance, Lipotoxicity and Metabolic Stress in Cultured Hepatocytes.

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Drug-induced lysosomal lipidosis: biochemical interpretations

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