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Early costochondral calcification in adolescent hyperthyroidism.

M O Senac, F A Lee, V Gilsanz

    Radiology
    |August 1, 1985
    PubMed
    Summary
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    Adolescents with hyperthyroidism show significantly higher rates of early costochondral calcification, indicating advanced bone maturation. This radiographic finding suggests a link between hyperthyroidism and accelerated skeletal development in young individuals.

    Area of Science:

    • Endocrinology
    • Radiology
    • Pediatrics

    Background:

    • Costochondral calcification is a normal part of aging.
    • Hyperthyroidism affects bone metabolism.

    Purpose of the Study:

    • To investigate the incidence of costochondral calcification in adolescents with hyperthyroidism.
    • To determine if hyperthyroidism is associated with accelerated bone maturation.

    Main Methods:

    • Retrospective study of 36 adolescent patients (ages 13-18) with hyperthyroidism.
    • Radiographic evaluation for costochondral calcification.
    • Comparison with a control group.

    Main Results:

    • 21 out of 32 (66%) thyrotoxic teenage girls exhibited costochondral calcification.

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  • Significantly higher incidence (66%) compared to controls (12%).
  • One male patient showed calcification, not observed in control males.
  • Conclusions:

    • Adolescents with hyperthyroidism demonstrate a higher incidence of early costochondral calcification.
    • This suggests advanced bone maturation in thyrotoxic adolescents.
    • Costochondral calcification may serve as a radiographic indicator of hyperthyroidism-related skeletal changes.