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Related Concept Videos

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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
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Related Experiment Video

Updated: Jun 13, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
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Overdose Detection Among High-Risk Opioid Users Via a Wearable Chest Sensor in a Supervised Injecting Facility:

Basak Tas1, Will Lawn2, Marianne Jauncey3

  • 1National Addiction Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

JMIR Research Protocols
|September 10, 2024
PubMed
Summary
This summary is machine-generated.

A new wearable biosensor, PneumoWave, is being developed to detect opioid overdose by measuring chest motion in real time. This technology aims to improve early intervention and reduce fatalities from opioid-induced respiratory depression (OIRD).

Keywords:
AustraliaUnited Statesalgorithmbiosensorchest biosensordetection algorithmdrug overdoseillicit drugsinjecting opioid usemedically supervised injection centermobile phonenaloxoneobservational designopioid induced respiratory depressionopioid overdoseopioid-related deathsoverdoserespiratory depressionsafe injecting facilitieswearablewearable devicewearable sensor

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Area of Science:

  • Wearable biosensor technology
  • Opioid overdose detection
  • Respiratory depression monitoring

Background:

  • Opioid overdose is a critical global health issue, causing over 100,000 deaths annually in the US.
  • Existing methods for overdose detection lack real-time capabilities, delaying crucial interventions.
  • The PneumoWave chest biosensor is a novel wearable device designed for continuous monitoring.

Purpose of the Study:

  • To develop and refine an algorithm for detecting opioid-induced respiratory depression (OIRD).
  • To differentiate OIRD from non-fatal opioid use patterns using chest motion data.
  • To assess participant acceptability of the PneumoWave chest biosensor.

Main Methods:

  • Observational study over 6 months involving participants at safe injecting facilities (SIFs).
  • Participants wear the PneumoWave biosensor during opioid injecting events to capture chest motion data.
  • Biosensor data is compared with staff-identified overdose events; acceptability assessed via questionnaires.

Main Results:

  • As of April 2024, 47 participants enrolled, with data from 1145 injecting events collected.
  • 10 overdose events have been recorded among participants (17 females, 30 males, average age 45).
  • Data analysis is ongoing to refine the overdose detection algorithm.

Conclusions:

  • The protocol supports the advancement of wearable technology for opioid overdose prevention in SIFs.
  • Chest wall movement data will train an algorithm for real-time overdose detection by the biosensor.
  • This study offers vital insights into OIRD and the potential of biosensors for timely intervention.