Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fast Decoupled and DC Powerflow01:24

Fast Decoupled and DC Powerflow

178
The fast decoupled power flow method addresses contingencies in power system operations, such as generator outages or transmission line failures. This method provides quick power flow solutions, essential for real-time system adjustments. Fast decoupled power flow algorithms simplify the Jacobian matrix by neglecting certain elements, leading to two sets of decoupled equations:
178
Refrigerators and Heat Pumps01:07

Refrigerators and Heat Pumps

2.2K
Refrigerators or heat pumps are heat engines operating in a reverse direction. For a refrigerator, the focus is on removing heat from a specific area, whereas, for a heat pump, the focus is on dumping heat into one particular area. A refrigerator (or heat pump) absorbs heat Qc from the cold reservoir at Kelvin temperature Tc and discards heat Qh to the hot reservoir at Kelvin temperature Th, while work W is done on the engine’s working substance.
A household refrigerator removes heat from...
2.2K
Power Factor Correction01:20

Power Factor Correction

161
The power transmission to a factory involves the transfer of apparent power, a combination of active and reactive power. The power factor measures how effectively electrical power is converted into useful work output. The ratio of the real power (KW) that does the work to the apparent power (KVA) supplied to the circuit.
161
Reducing Line Loss01:18

Reducing Line Loss

150
In a three-phase circuit, line loss is an indicator of energy dissipated as heat due to the resistance of transmission lines. To address this, incorporating transformers into the system—a step-up transformer at the source and a step-down transformer at the load—is a strategic solution. Two three-phase transformers are introduced to improve this.
With a step-up transformer at the source, the voltage is increased, thereby reducing the current in the transmission lines since power loss...
150
Design Example: Capacitance Multiplier Circuit01:20

Design Example: Capacitance Multiplier Circuit

730
In integrated circuit technology, a capacitance multiplier is often utilized to produce a larger capacitance value when a small physical capacitance falls short. This is achieved by a circuit that multiplies capacitance values by a factor of up to 1000, such that a 10-pF capacitor can replicate the performance of a 100-nF capacitor.
The circuit illustrated in Figure 1 below incorporates two op-amps, with the first operating as a voltage follower and the second acting as an inverting amplifier.
730

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Computational Nutrition in Practice: Challenges and Opportunities From an Early-Career Perspective.

The Journal of nutrition·2026
Same author

The P4D Dashboard: A Platform for Monitoring Clinical Studies.

Studies in health technology and informatics·2025
Same author

Quantized Inverse Design for Photonic Integrated Circuits.

ACS omega·2025
Same author

Genie: the first open-source ISO/IEC encoder for genomic data.

Communications biology·2024
Same author

Validation of the predictive value of BDNF -87 methylation for antidepressant treatment success in severely depressed patients-a randomized rater-blinded trial.

Trials·2024
Same author

GVC: efficient random access compression for gene sequence variations.

BMC bioinformatics·2023
Same journal

OpenIMC: an open-source platform for analyzing single-cell and spatial proteomics by imaging mass cytometry.

BMC bioinformatics·2026
Same journal

NAP: an open source pipeline for cross-domain microbiome profiling using Nanopore sequencing-derived amplicon data.

BMC bioinformatics·2026
Same journal

SurvGME: an R package for survival analysis with graphical and measurement error models.

BMC bioinformatics·2026
Same journal

SimMapNet: a Bayesian framework for gene regulatory network inference using gene ontology similarities as external hint.

BMC bioinformatics·2026
Same journal

Dual channel drug-drug interactions extraction based on cross attention.

BMC bioinformatics·2026
Same journal

FeSseqdb: a curated sequence-level database and interpretable machine learning framework for identifying iron-sulfur proteins.

BMC bioinformatics·2026
See all related articles

Related Experiment Video

Updated: Jun 13, 2025

Modeling and Experimental Analysis of the Single-Shaft Coaxial Motor-Pump Assembly in Electrohydrostatic Actuators
08:59

Modeling and Experimental Analysis of the Single-Shaft Coaxial Motor-Pump Assembly in Electrohydrostatic Actuators

Published on: June 13, 2022

2.5K

HiCMC: High-Efficiency Contact Matrix Compressor.

Yeremia Gunawan Adhisantoso1, Tim Körner2, Fabian Müntefering2

  • 1Institut für Informationsverarbeitung and L3S Research Center, Leibniz University Hannover, Hannover, Germany. adhisant@tnt.uni-hannover.de.

BMC Bioinformatics
|September 10, 2024
PubMed
Summary
This summary is machine-generated.

We developed High-Efficiency Contact Matrix Compressor (HiCMC), a novel method for compressing large Hi-C datasets. HiCMC significantly improves compression efficiency by modeling chromosome structure, aiding biological research.

Keywords:
3CCompressionContact matrixHi-C

More Related Videos

A 100 KW Class Applied-field Magnetoplasmadynamic Thruster
11:47

A 100 KW Class Applied-field Magnetoplasmadynamic Thruster

Published on: December 22, 2018

9.0K
Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System
09:56

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Published on: December 23, 2022

1.6K

Related Experiment Videos

Last Updated: Jun 13, 2025

Modeling and Experimental Analysis of the Single-Shaft Coaxial Motor-Pump Assembly in Electrohydrostatic Actuators
08:59

Modeling and Experimental Analysis of the Single-Shaft Coaxial Motor-Pump Assembly in Electrohydrostatic Actuators

Published on: June 13, 2022

2.5K
A 100 KW Class Applied-field Magnetoplasmadynamic Thruster
11:47

A 100 KW Class Applied-field Magnetoplasmadynamic Thruster

Published on: December 22, 2018

9.0K
Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System
09:56

Mechanostimulation of Multicellular Organisms Through a High-Throughput Microfluidic Compression System

Published on: December 23, 2022

1.6K

Area of Science:

  • Genomics
  • Bioinformatics
  • Molecular Biology

Background:

  • Chromosome organization is crucial for DNA replication, regulation, and transcription.
  • Hi-C studies capture genome-wide chromosome conformation but generate massive datasets.
  • Dynamic changes in chromosome structure necessitate frequent data collection, increasing storage demands.

Purpose of the Study:

  • To present a novel, efficient data compression approach for Hi-C data.
  • To address the challenge of large data storage in chromosome conformation studies.

Main Methods:

  • Developed High-Efficiency Contact Matrix Compressor (HiCMC).
  • HiCMC models intrinsic structures within Hi-C contact matrices, including compartments and domains.
  • Integrated domain-specific information into compressed data for accelerated downstream analysis.

Main Results:

  • HiCMC achieved superior compression rates compared to state-of-the-art methods.
  • Outperformed CMC by approximately 8% and other methods (cooler, LZMA, bzip2) by over 50%.
  • Demonstrated effectiveness across various cell lines and contact matrix resolutions.

Conclusions:

  • HiCMC offers a significant advancement in Hi-C data compression.
  • Leverages inherent properties of contact matrices for improved efficiency.
  • Provides a valuable tool for genomic research, available at https://github.com/sXperfect/hicmc.