Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Life Histories

Life Histories

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mapping the spatiotemporal continuum of structural connectivity development across the human connectome in youth.

Nature communications·2026

Same author

Homologous specialization of arcuate fasciculus ventrolateral frontal connectivity in marmosets and humans.

Proceedings of the National Academy of Sciences of the United States of America·2026

Same author

Developmental variations in recurrent spatiotemporal brain propagations from childhood to adulthood.

Nature communications·2026

Same author

Is Pearson's correlation coefficient enough for functional connectivity in fMRI?

Imaging neuroscience (Cambridge, Mass.)·2025

Same author

Connectome-based symptom mapping and in silico related gene expression in children with autism and/or attention-deficit/hyperactivity disorder.

Molecular psychiatry·2025

Same author

Human cortex organizes dynamic co-fluctuations along sensation-association axis.

bioRxiv : the preprint server for biology·2025

Same journal

Layered social competition coordinates reproductive hierarchy formation in ants.

bioRxiv : the preprint server for biology·2026

Same journal

Combination epigenetic-targeted therapy increases the immunogenicity of poorly immunogenic sarcomas.

bioRxiv : the preprint server for biology·2026

Same journal

Loss of LanC-like proteins delays post-injury regeneration of aging skeletal muscles.

bioRxiv : the preprint server for biology·2026

Same journal

Integrative Transfer Network: Deep Transfer Learning Across Populations and Prediction Targets.

bioRxiv : the preprint server for biology·2026

Same journal

Confidence-supported label-free metabolic imaging with FPhaS phase autofluorescence microscopy.

bioRxiv : the preprint server for biology·2026

Same journal

Sequence-encoded autoinhibition couples mRNA decapping activity to phase separation.

bioRxiv : the preprint server for biology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 1, 2026

Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques

Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques

Published on: April 22, 2010

Brain Charts for the Rhesus Macaque Lifespan.

S Alldritt¹, J S B Ramirez^2,3, R Vos de Wael²

¹Center for the Integrative Developmental Neuroscience, Child Mind Institute.

Biorxiv : the Preprint Server for Biology

|September 11, 2024

Summary

This summary is machine-generated.

This study created the first normative brain growth charts for rhesus macaques, essential for understanding neurodevelopment and aging in this primate model. These charts aid cross-species research, advancing translational neuroscience.

More Related Videos

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

Published on: July 17, 2020

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

Related Experiment Videos

Last Updated: May 1, 2026

Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques

Multicolor Flow Cytometry Analyses of Cellular Immune Response in Rhesus Macaques

Published on: April 22, 2010

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

A MRI-Based Toolbox for Neurosurgical Planning in Nonhuman Primates

Published on: July 17, 2020

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

Area of Science:

Neuroscience
Developmental Biology
Comparative Anatomy

Background:

Human brain development has reference standards, but nonhuman primate (NHP) models lack similar growth charts.
Rhesus macaques are valuable NHP models due to similarities with humans in brain anatomy, behavior, and genetics.
Understanding NHP brain development is crucial for translational neuroscience.

Purpose of the Study:

To establish normative growth charts for brain structure across the rhesus macaque lifespan.
To map developmental trajectories of brain volume, cortical thickness, and surface area.
To facilitate cross-species translational research by providing a comparative resource.

Main Methods:

Aggregated 1,522 MRI scans from 1,024 rhesus macaques from PRIME-DE and other sources.
Mapped non-linear developmental trajectories for global and regional brain structural changes.
Developed normative charts with centile scores for macaque brain structures.

Main Results:

Provided normative growth charts for rhesus macaque brain structures across the lifespan.
Identified key developmental milestones from prenatal stages through aging.
Revealed both species-specific and human-comparable brain maturation patterns.

Conclusions:

The developed charts are a valuable resource for NHP studies, especially those with limited sample sizes.
The findings enhance understanding of neurodevelopment and aging in macaques.
An interactive open resource supports cross-species comparisons to advance translational neuroscience.