Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Association Areas of the Cortex01:21

Association Areas of the Cortex

5.2K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
5.2K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

392
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
392
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

444
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
444
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

3.6K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
3.6K
Working Memory01:24

Working Memory

147
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
147
Lobes of the Cerebrum01:22

Lobes of the Cerebrum

586
The cerebral cortex, a critical structure of the brain, is intricately divided into two hemispheres, each consisting of four distinct lobes: occipital, temporal, frontal, and parietal. These lobes function cooperatively to regulate various cognitive and sensory functions, forming the basis of our complex neural capabilities.
Frontal lobe
The frontal lobes, located behind the forehead, are the command center of our brain, controlling personality, intelligence, and voluntary muscle movements....
586

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Limits of V4 perisaccadic firing rate modulations in explaining perceptual mislocalization.

bioRxiv : the preprint server for biology·2026
Same author

A population readout of extrastriate activity reveals biased and smoothed temporal representations across saccades.

bioRxiv : the preprint server for biology·2026
Same author

A Report of Lumbar Disk Herniation Treatment Outcomes: Percutaneous Laser Disk Decompression vs Open Microdiscectomy.

Basic and clinical neuroscience·2026
Same author

Sorghum Starch and Protein Digestibility: Mechanisms, Modifications, and Health Implications.

Foods (Basel, Switzerland)·2026
Same author

Retinal microvasculature changes in long-term consumption of hydroxychloroquine.

Scientific reports·2026
Same author

Quantitative imaging for assessing uveitis activity: A comprehensive review.

Survey of ophthalmology·2026
Same journal

A human-specific genetic modifier reconfigures large-scale cortical network dynamics underlying behavioral performance.

bioRxiv : the preprint server for biology·2026
Same journal

<i>Staphylococcus aureus</i> uses a eukaryotic-like uridyltransferase to make UDP-GlcNAc for cell wall synthesis.

bioRxiv : the preprint server for biology·2026
Same journal

Dynamic redistribution of eIF4F controls cap-dependent translation initiation.

bioRxiv : the preprint server for biology·2026
Same journal

When does additional information improve accuracy of RNA secondary structure prediction?

bioRxiv : the preprint server for biology·2026
Same journal

Normative brain-state trajectories reveal deviation from healthy aging in Alzheimer's disease.

bioRxiv : the preprint server for biology·2026
Same journal

Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation.

bioRxiv : the preprint server for biology·2026
See all related articles

Related Experiment Video

Updated: Jun 13, 2025

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

18.7K

Prefrontal working memory signal controls phase-coded information within extrastriate cortex.

Mohsen Parto-Dezfouli1,2, Isabel Vanegas3, Mohammad Zarei4

  • 1Max Planck Institute for Biological Cybernetics, 72076 Tübingen, Germany.

Biorxiv : the Preprint Server for Biology
|September 11, 2024
PubMed
Summary
This summary is machine-generated.

Working memory (WM) enhances visual processing by inducing brain oscillations in V4 neurons. Prefrontal cortex signals are crucial for this WM-driven boost in phase coding, supporting a sensory recruitment theory.

Keywords:
neural oscillationsneural phase codeprefrontal cortextop-down controlworking memory

More Related Videos

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex
09:00

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

Published on: April 15, 2015

12.3K
Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis
10:33

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

12.8K

Related Experiment Videos

Last Updated: Jun 13, 2025

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication
09:26

Disruption of Frontal Lobe Neural Synchrony During Cognitive Control by Alcohol Intoxication

Published on: February 6, 2019

18.7K
Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex
09:00

Investigating the Function of Deep Cortical and Subcortical Structures Using Stereotactic Electroencephalography: Lessons from the Anterior Cingulate Cortex

Published on: April 15, 2015

12.3K
Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis
10:33

Correlating Behavioral Responses to fMRI Signals from Human Prefrontal Cortex: Examining Cognitive Processes Using Task Analysis

Published on: June 20, 2012

12.8K

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Visual Processing

Background:

  • Working memory (WM) is crucial for cognitive functions, including visual processing.
  • The prefrontal cortex (PFC) plays a key role in WM, but its precise influence on sensory areas remains unclear.
  • Understanding how PFC modulates sensory representations is vital for theories of cognition.

Purpose of the Study:

  • To investigate how WM, mediated by the PFC, influences visual signal representation in V4 neurons.
  • To explore the neural mechanisms underlying WM's benefits for visual processing.

Main Methods:

  • Recorded V4 neuronal activity in macaques during a WM task.
  • Analyzed neuronal oscillations and spike timing relative to oscillations (phase coding).
  • Used pharmacological inactivation of the Frontal Eye Field (FEF) in the PFC.

Main Results:

  • WM induced strong gamma oscillations in V4.
  • Action potential timing relative to gamma oscillations encoded visual information (phase coding).
  • FEF inactivation abolished the WM-driven enhancement of phase coding.
  • V4 firing rates correlated with WM-induced oscillatory changes.

Conclusions:

  • PFC signals are necessary for WM to enhance phase coding of visual information in V4.
  • WM recruits sensory areas by inducing oscillations, supporting a sensory recruitment theory of WM through neural coherence.