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Related Concept Videos

Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Skin Cancer01:30

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Hair and hair follicles are integral components of the integumentary system. Hair is a filamentous structure composed mainly of a protein called keratin. It is found on the surface of the skin throughout the body, except for areas such as the palms of the hands and soles of the feet.
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Updated: Jun 13, 2025

Cheek Injection Model for Simultaneous Measurement of Pain and Itch-related Behaviors
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[A man with pruritic papules].

Daan J W Rauwerdink1,2, Thijs Ruiken1, Deepak M W Balak1

  • 1LUMC, afd. Huidziekten, Leiden.

Nederlands Tijdschrift Voor Geneeskunde
|September 11, 2024
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Summary
This summary is machine-generated.

A simple skin test using a medical marker and alcohol can diagnose scabies. This burrow ink test accurately identifies scabies in patients presenting with itchy papules.

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Area of Science:

  • Dermatology
  • Medical Diagnostics
  • Parasitology

Background:

  • Scabies is a contagious skin infestation caused by the mite Sarcoptes scabiei.
  • Diagnosis can be challenging, often relying on clinical presentation and microscopic identification of mites or eggs.
  • Generalized itch and papules are common symptoms requiring accurate diagnostic methods.

Observation:

  • A patient presented with widespread itching and hand papules.
  • A purple medical skin marker was applied to a papule.
  • The ink was wiped away with alcohol-gauze, revealing an ink-filled burrow.

Findings:

  • The presence of an ink-filled burrow confirmed a positive burrow ink test.
  • This diagnostic finding led to a clinical diagnosis of scabies.
  • The burrow ink test offers a rapid and accessible method for scabies diagnosis.

Implications:

  • The burrow ink test provides a valuable tool for clinicians diagnosing scabies.
  • This method can aid in early detection and prompt treatment of scabies infestations.
  • Improved diagnostic accuracy can reduce the spread of scabies in community settings.