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Modification of the nucleolar structure of the rat oocyte observed just before maturation

C Merveille, E Baeckeland, A M Renard

Annals of the New York Academy of Sciences

|January 1, 1985

Abstract:

Oocytes removed from antral follicles of 28- to 30-day-old rats treated with FSH (Folligon) show cavities and vesicles in the nucleoli. Repeated injections of Folligon significantly increase the frequency of these nucleolar inclusions. A possible relationship between intranucleolar cavities and rRNA metabolism has been suggested to account for this occurrence.

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