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Updated: Jun 13, 2025

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A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
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Neighborhood Child Opportunity and Preterm Birth Rates by Race and Ethnicity
Candice Belanoff1, Adriana Black2, Collette N Ncube3
1Department of Community Health Sciences, Boston University School of Public Health, Boston, Massachusetts.
JAMA Network Open
|September 11, 2024
Summary
Infants in low opportunity neighborhoods face higher preterm birth risks, highlighting neighborhood factors in racial inequities. Addressing neighborhood conditions may reduce preterm birth disparities.
Area of Science:
- Public Health
- Epidemiology
- Social Determinants of Health
Background:
- Preterm birth rates are significantly higher for non-Hispanic Black infants compared to non-Hispanic White infants in the US.
- Individual factors do not fully explain these preterm birth disparities.
- Neighborhood context, influenced by historical structural racism, may be a key factor in understanding these inequities.
Purpose of the Study:
- To assess the association between neighborhood opportunity levels, using the Child Opportunity Index (COI), and the incidence of preterm birth in Massachusetts.
- To investigate the role of neighborhood context in preterm birth disparities.
Main Methods:
- Cross-sectional, population-based study utilizing Massachusetts birth certificates (2011-2015).
- Linked birth data with US Census tract-level Child Opportunity Index (COI) data.
- Employed log binomial regression and generalized estimating equations to analyze associations.
Main Results:
- Infants born in very low opportunity neighborhoods showed a higher prevalence of preterm birth (adjusted PR, 1.16; 95% CI, 1.10-1.23).
- Over half of infants born to non-Hispanic Black and Hispanic birthing parents resided in very low opportunity neighborhoods.
- Crude models indicated a 44% higher prevalence of preterm birth in the lowest versus highest opportunity neighborhoods.
Conclusions:
- Exposure to very low opportunity neighborhoods is associated with an elevated risk of preterm birth.
- The disproportionate exposure of racial and ethnic minority groups to low opportunity neighborhoods suggests a modifiable factor contributing to preterm birth inequities.
- Interventions targeting neighborhood opportunity are warranted to address racial and ethnic disparities in preterm birth.
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