Roadmap to a Global Template for Implementation of Ototoxicity Management for Cancer Treatment

Katharine Fernandez1, Alex Hoetink2,3,4,5, Dawn Konrad-Martin6,7

  • 1Division of Intramural Research, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, Maryland, USA.

Ear and Hearing
|September 12, 2024
PubMed

Insights

Cancer treatment can cause hearing and balance problems. This study proposes a roadmap for ototoxicity management (OtoM) to improve patient quality-of-life through standardized care.

Area of Science:

  • Oncology
  • Audiology
  • Otolaryngology

Background:

  • Ototoxicity, a side effect of cancer treatments like chemotherapy and radiation, significantly impacts patient quality-of-life.
  • Hearing loss, tinnitus, and vestibular dysfunction are common consequences, yet standardized clinical management is lacking.
  • The physical, socioeconomic, and psychological effects necessitate a structured approach to ototoxicity management (OtoM).

Purpose of the Study:

  • To review current evidence on cancer treatment-related ototoxicity.
  • To propose a roadmap for developing and implementing standardized OtoM programs.
  • To address the needs of patients, survivors, and caregivers throughout cancer care.

Main Methods:

  • Review of existing evidence on ototoxicity and its management.
  • Identification of strategic areas for advancing OtoM.
  • Proposal of near-term and longer-term goals for OtoM implementation.

Main Results:

  • Lack of widely adopted standards for clinical management of cancer treatment-related ototoxicity.
  • Identification of five strategic areas to advance OtoM: beneficiary engagement, workforce enhancement, program development, policy/funding, and research.
  • A need for consensus recommendations and a roadmap to guide OtoM development and adoption.

Conclusions:

  • Standardized OtoM is crucial for improving outcomes for cancer patients and survivors.
  • A strategic roadmap is proposed to guide the worldwide adoption of OtoM.
  • Multifaceted efforts are required to integrate effective OtoM into cancer care.

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