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Updated: Jun 13, 2025

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[Hypertension and menopause: physiopathology and impact of the hormonal therapy]
Anaïs Juillet1, Bénédicte Le Tinier2, Isabelle Streuli3
1Service de médecine interne générale, Hôpitaux universitaires de Genève, 1211 Genève 14.
Abstract:
Menopause, as a consequence of ovarian follicular decline, induces estrogen deficiency and metabolic changes that increase the cardiovascular risk in women. In particular, there is an increase in blood pressure during menopause. Menopausal hormonal therapy can be prescribed to women with symptoms of menopause to improve their quality of life. This article reviews the current literature on the pathophysiological mechanisms that explain blood pressure changes at menopause and describes the impact of menopausal hormone therapy on blood pressure.
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