Management Strategies for Hypertensive Crisis: A Systematic Review

Naveed N Khan1, Elaf J Zurayyir2, Afyaa M Alghamdi3

  • 1Internal Medicine, King Salman Armed Forces Hospital, Tabuk, SAU.

Cureus
|September 12, 2024
PubMed

Insights

A hypertensive crisis, a sudden rise in blood pressure to 180/120 mmHg or higher, requires immediate medical attention. This study reviews management strategies for this life-threatening emergency to improve patient outcomes.

Area of Science:

  • Cardiology
  • Emergency Medicine
  • Clinical Pharmacy

Background:

  • A hypertensive crisis is a critical medical emergency characterized by a sudden, significant elevation in blood pressure (≥180/120 mmHg).
  • It poses a severe risk for life-threatening complications, including myocardial infarction, stroke, and end-organ damage.
  • Poor medication adherence and low follow-up rates contribute to high morbidity, mortality, and recurrence rates.

Purpose of the Study:

  • To investigate and synthesize current management strategies for hypertensive crisis.
  • To identify evidence-based approaches for controlling severe hypertension in acute settings.

Main Methods:

  • A systematic review of English-language articles published between 2010 and 2024.
  • Analysis of 15 selected articles focusing on hypertensive crisis diagnosis and management.
  • Inclusion criteria specified investigative studies, data integrity, and management reports.

Main Results:

  • Acute severe hypertension is linked to substantial mortality and morbidity, especially with end-organ damage.
  • Current treatment protocols for hypertensive crisis vary significantly across hospital units and lack standardized, evidence-based guidance.
  • Specific interventions like intravenous esmolol for aortic dissection and vasodilators (nitroglycerin, nitroprusside) are highlighted.

Conclusions:

  • Effective management of hypertensive crisis requires tailored, evidence-based protocols, particularly in critical care settings.
  • Standardization of blood pressure targets and treatment algorithms is crucial to mitigate risks associated with acute severe hypertension.
  • Further research is needed to establish clear guidelines for managing hypertensive emergencies and improve patient adherence and follow-up.

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