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Epstein-Barr Virus-Negative Plasmablastic Lymphoma Post-liver Transplantation
Jonathan K Lin1, Lafaine Grant1
1Division of Digestive and Liver Diseases, UT Southwestern Medical Center, Dallas, TX.
ACG Case Reports Journal
|September 12, 2024
Summary
Plasmablastic lymphoma (PBL) is a rare, aggressive B-cell cancer after organ transplants. This case highlights an Epstein-Barr virus-negative PBL occurring over six years post-liver transplant, emphasizing its challenging diagnosis and poor prognosis.
Area of Science:
- Oncology
- Immunology
- Transplantation Medicine
Background:
- Post-transplant lymphoproliferative disorders (PTLD) are serious complications following organ transplantation.
- Plasmablastic lymphoma (PBL) is a rare and aggressive subtype of PTLD, often associated with the Epstein-Barr virus.
- PBL post-liver transplantation is exceptionally rare, with limited documented cases.

