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Related Experiment Video

Updated: May 3, 2026

Stereotactic Radiosurgery for Gynecologic Cancer
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Optical Surface Management System and BladderScan for Patient Setup During Radiotherapy of Postoperative Prostate

Hao Chen1, Yandong Liu1, Songbin Qin1

  • 1Department of Radiation Oncology First Affiliated Hospital of Soochow University, Suzhou 215000, China.

Biomed Research International
|September 12, 2024
PubMed
Summary

A new setup method combining Optical Surface Management System (OSMS) and BladderScan significantly improves patient setup accuracy in prostate cancer radiotherapy. This zero-dose technique enhances precision by better reproducing bladder volume, reducing errors compared to conventional methods.

Keywords:
BladderScanCBCTDice similarity coefficientoptical surface imagingreal-time setup

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Area of Science:

  • Radiation oncology
  • Medical physics
  • Prostate cancer treatment

Background:

  • Radiotherapy precision for prostate cancer is challenged by setup errors and bladder volume changes.
  • Daily cone beam computed tomography (CBCT) corrects setup errors but raises concerns about peripheral dose and workload.
  • A zero-dose, noninvasive method is needed to accurately reproduce bladder volume and improve patient setup.

Purpose of the Study:

  • To evaluate if combining Optical Surface Management System (OSMS) and BladderScan improves setup accuracy in postoperative prostate cancer radiotherapy.
  • To determine if this combined method accurately reproduces bladder volume.
  • To guide clinical target volume (CTV) to planning target volume (PTV) margins.

Main Methods:

  • A prospective study comparing a combined OSMS and BladderScan setup method (experimental group) with a conventional skin marker method (control group).
  • Setup errors (lateral, longitudinal, vertical, Pitch, Yaw, Roll) were analyzed using CBCT verification.
  • Bladder volume concordance was assessed using Dice Similarity Coefficient (DSC) and volume differences between CBCT and planning CT.

Main Results:

  • The experimental group showed significantly reduced setup errors in all directions (e.g., Vrt: 0.17 vs. 0.25 cm) and rotational errors (e.g., Pitch: 0.18° vs. 0.96°) compared to the control group (P < 0.01).
  • Bladder volume concordance was superior in the experimental group (DSC: 92.52% vs. 62.98%) with smaller volume differences (39.99 cm³ vs. 273.89 cm³).
  • All performance indicators demonstrated statistically significant improvements (P < 0.01).

Conclusions:

  • The combined OSMS and BladderScan setup method is validated by CBCT for improving accuracy in postoperative prostate cancer radiotherapy.
  • This technique offers enhanced setup precision compared to conventional methods.
  • The findings support the use of this method for optimizing radiotherapy delivery and margins.