Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

143
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
143

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intertriginous Secondary Syphilis: A Case Report of a Rare Presentation.

The American Journal of dermatopathology·2026
Same author

Proliferative Neurocristic Hamartoma Arising From a Congenital Melanocytic Nevus: A Case Report.

Journal of cutaneous pathology·2025
Same author

Vesicular syphilis mimicking subepidermal immunobullous disease: a case report.

International journal of dermatology·2024
Same author

Photoaging features of melasma: An in vivo layered and quantitative analysis using computer-aided detection of cellular resolution full-field optical coherence tomography.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Should antituberculosis treatment be prescribed in erythema induratum? A case-control and incidence correlation study in Taiwan, 2001-2020.

Clinical and experimental dermatology·2024
Same author

Generalized early inflammatory morphea mimicking interstitial T-cell lymphoma: A diagnostic pitfall.

Journal of cutaneous pathology·2023

Related Experiment Video

Updated: May 5, 2026

Murine Skin Transplantation
06:42

Murine Skin Transplantation

Published on: January 16, 2008

22.5K

Human cutaneous pythiosis: A case report.

Nutpeera Nutthapan1, Wuttinee Sutichaiworapong2, Yu-Hung Wu3

  • 1Division of Dermatology, Department of Internal Medicine, Sisaket Hospital, Sisaket, Thailand.

Journal of Cutaneous Pathology
|September 12, 2024
PubMed
Summary

Human pythiosis, a rare infection caused by Pythium insidiosum, can affect the skin. This case highlights its distinct histopathology in a thalassemic patient, aiding diagnosis.

Keywords:
Pythiumhistopathologyhuman cutaneous pythiosispathology

More Related Videos

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

24.5K
Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites
08:46

Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites

Published on: May 18, 2016

17.3K

Related Experiment Videos

Last Updated: May 5, 2026

Murine Skin Transplantation
06:42

Murine Skin Transplantation

Published on: January 16, 2008

22.5K
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
10:27

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis

Published on: December 15, 2011

24.5K
Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites
08:46

Myeloid Cell Isolation from Mouse Skin and Draining Lymph Node Following Intradermal Immunization with Live Attenuated Plasmodium Sporozoites

Published on: May 18, 2016

17.3K

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Human pythiosis is a rare but severe infection caused by the fungus-like organism Pythium insidiosum.
  • Cutaneous pythiosis is an uncommon clinical manifestation, often occurring in tropical regions.
  • The histopathological features of cutaneous pythiosis are not well-documented.

Observation:

  • A case of cutaneous pythiosis in an adult agricultural worker with thalassemia is presented.
  • The patient exhibited a painful, erythematous plaque on the leg over two months.
  • Histopathology revealed eosinophilic granulomatous inflammation with the Splendore-Hoeppli phenomenon.

Findings:

  • Definitive diagnosis was confirmed via histopathology and detection of anti-Pythium insidiosum antibodies using ELISA.
  • The study details the characteristic histopathological findings in this rare cutaneous form of pythiosis.
  • The Splendore-Hoeppli phenomenon was noted, similar to entomophthoromycosis.

Implications:

  • This case enhances understanding of cutaneous pythiosis histopathology.
  • Early diagnosis and treatment of pythiosis are crucial for patient outcomes.
  • Further research into the link between pythiosis and hemoglobinopathies may be warranted.