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Related Experiment Video

Updated: Jun 13, 2025

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

Equine Melanoma Updates.

Anna R Hollis¹

¹Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK.

The Veterinary Clinics of North America. Equine Practice

|September 12, 2024

Summary

Gray horses commonly develop melanomas, with 80% affected by age 15. These tumors, once thought benign, can metastasize in up to 66% of cases, necessitating treatment like surgical resection.

Area of Science:

Veterinary dermatology
Equine oncology

Background:

Melanomas are highly prevalent in aging gray horses, affecting 80% by 15 years.
Historically viewed as benign, equine melanomas have a significant metastatic potential.

Purpose of the Study:

To highlight the prevalence and potential complications of melanomas in gray horses.
To discuss current treatment considerations for equine melanoma.

Main Methods:

Review of existing literature on equine melanoma.
Analysis of clinical observations regarding melanoma behavior and treatment.

Main Results:

Up to 66% of equine melanomas can metastasize.
Lesions can cause local issues like abscessation and functional impairment.

Keywords:

Horse Melanomatosis Tumour

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Surgical resection is the preferred treatment when feasible.

Conclusions:

Equine melanomas require careful monitoring due to metastatic risk.
Prompt surgical intervention is recommended for treatable lesions.
Further research into melanoma treatment and prevention is warranted.