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Effect of smoking on the recurrence and progression of non-muscle-invasive bladder cancer

  • 0Institute of Urology, Lanzhou University Second Hospital, Chengguan District, No.82 Linxia Road, Lanzhou, 730030, People's Republic of China.
Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico +

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September 12, 2024

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September 12, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Smoking significantly increases the risk of recurrence and progression in patients with non-muscle-invasive bladder cancer (NMIBC). Quitting smoking improves quality of life for these patients.

Area Of Science

  • Urology
  • Oncology
  • Public Health

Background

  • Smoking is a primary risk factor for bladder cancer.
  • The effect of smoking on non-muscle-invasive bladder cancer (NMIBC) recurrence and progression is debated.
  • Understanding this link is crucial for patient management.

Purpose Of The Study

  • To comprehensively review existing literature on smoking's impact on NMIBC recurrence and progression.
  • To provide evidence for smoking cessation strategies in NMIBC patients.
  • To identify gaps in current research.

Main Methods

  • Systematic literature search of PubMed, Web of Science, and Embase up to April 2024.
  • Analysis of 24 included studies.
  • Evaluation of study findings, deficiencies, and research gaps.

Main Results

  • 14 studies indicated smoking promotes NMIBC recurrence and progression.
  • 10 studies found no significant effect of smoking on NMIBC outcomes.
  • Conflicting evidence highlights the need for further investigation.

Conclusions

  • Smoking is associated with increased NMIBC recurrence and progression.
  • Smoking cessation positively impacts health-related quality of life in NMIBC patients.
  • High-quality prospective cohort or randomized controlled studies are needed.

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