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Damage control surgery in non-traumatic abdominal emergencies: prognostic value of SOFA, APACHEII, and Mannheim
Roberto Rasslan1, Fábio de Oliveira Ferreira2, Jeammy Andrea Perez Parra2
1Departament of Surgery, Division of General Surgery and Trauma, Universidade de São Paulo, Av. Dr Enéas de Carvalho Aguiar, no. 255, 8th. Floor, São Paulo, Brazil. robertorasslan@uol.com.br.
Abstract:
This study aimed to analyze the prognostic value of the SOFA, APACHE II, and MPI (Mannheim Peritonitis Index) scores in the indication for Damage Control Surgery (DCS) in non-trauma. Retrospective analysis of patients undergoing DCS between 2014 and 2019. SOFA and APACHE II scores were calculated using parameters preceding DCS, while MPI was based on surgical descriptions. Statistical analysis: Qualitative variables were compared using the Chi-square test or Fisher's exact test, and quantitative variables using Pearson's correlation coefficient. The Student's T test was employed for mean comparisons. The sample comprised 104 patients (59 males), with a median age of 63.5 years, of whom 52 (50%) were ASA IV. Operative findings leading to DCS included peritonitis (54; 51.9%), intestinal ischemia (39; 37.5%), inability to close the abdomen (8; 7.6%), and bleeding (3; 2.9%). The mortality rate was 75% (78/104). Thirty patients (28.8%) died after DCS; the remainder underwent one (35; 33.6%), two (21; 20.2%); three (8; 7.7%), and four or more (10;9.7%) revision procedures. The median lengths of ICU and hospital stays were 12.5 and 20.5 days, respectively. The median score values were as follows: SOFA: 12 (0-38), APACHE II: 25 (2-47), and MPI: 26 (8-43). Besides ASA classification (p = 0.03), mortality risk was influenced by: age (≤ 65 years vs. > 65 years; p = 0.04), SOFA (≤ 10 vs. > 10; p = 0.03), APACHE II (≤ 25 vs. > 25; p = 0.04), and MPI (≤ 25 vs. > 25; p = 0.003). The SOFA, APACHE II, and MPI scores proved to be valuable tools in the prognostic assessment of patients undergoing DCS in non-traumatic abdominal emergencies.
Insights
Prognostic scores like SOFA, APACHE II, and Mannheim Peritonitis Index (MPI) effectively predict outcomes for patients undergoing Damage Control Surgery (DCS) in non-trauma cases. These scores aid in assessing mortality risk and guiding surgical decisions for abdominal emergencies.
Area of Science:
- Surgical outcomes research
- Critical care medicine
- Prognostic modeling
Background:
- Damage Control Surgery (DCS) is crucial for non-trauma abdominal emergencies.
- Accurate prognostic assessment is vital for patient management and surgical planning.
- Existing scoring systems require evaluation for their utility in DCS contexts.
Purpose of the Study:
- To evaluate the prognostic value of Sequential Organ Failure Assessment (SOFA), APACHE II, and Mannheim Peritonitis Index (MPI) scores.
- To determine the predictive accuracy of these scores for mortality in patients undergoing DCS for non-traumatic abdominal conditions.
- To assess the utility of these scores in guiding surgical decisions for DCS.
Main Methods:
- Retrospective analysis of 104 patients undergoing DCS between 2014-2019.
- SOFA and APACHE II scores calculated pre-DCS; MPI based on surgical descriptions.
- Statistical analysis included Chi-square, Fisher's exact, Pearson's correlation, and Student's T tests.
Main Results:
- High mortality rate (75%) observed post-DCS.
- SOFA, APACHE II, and MPI scores significantly correlated with mortality risk (p<0.05).
- Age and ASA classification also influenced mortality risk.
Conclusions:
- SOFA, APACHE II, and MPI scores are valuable prognostic tools for patients undergoing DCS in non-traumatic abdominal emergencies.
- These scores can aid in risk stratification and clinical decision-making.
- Further research may refine the application of these scores in DCS protocols.
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