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Published on: April 7, 2021
SARS‑CoV‑2 infection exacerbates diaphragmatic eventration: A case report
1Department of Respiratory and Critical Care Medicine, The Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang 315040, P.R. China.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection worsened congenital localized diaphragmatic eventration (DE) to complete DE. This case highlights the potential for COVID-19 to accelerate rare disease progression.
Area of Science:
- Medical Case Study
- Pulmonology
- Thoracic Surgery
Background:
- Adult congenital localized diaphragmatic eventration (DE) is rare and often asymptomatic.
- Progression from localized to complete DE is uncommon.
- The COVID-19 pandemic has strained healthcare and exacerbated underlying conditions.
Observation:
- A patient with congenital localized DE experienced worsening symptoms post-SARS-CoV-2 infection.
- Symptoms included persistent cough, chest tightness, and abdominal distension.
- Imaging confirmed progression to complete left-sided DE.
Findings:
- SARS-CoV-2 infection exacerbated pre-existing localized DE to complete DE.
- The progression led to significant, symptomatic respiratory and abdominal issues.
- Surgical intervention (diaphragmatic plication) was successful.
Implications:
- COVID-19 can accelerate the progression of rare, asymptomatic conditions like DE.
- This case underscores the importance of monitoring chronic conditions during viral infections.
- Early diagnosis and surgical management are crucial for favorable outcomes in advanced DE.
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