[Metabolic syndrome in clinical psychiatric practice]
1Saint Petersburg State University, St. Petersburg, Russia.
Abstract:
A literature review in PubMed and Google databases was performed. Inclusion criteria: randomized clinical trials, meta-analyses and systematic reviews, relevant full-text articles on metabolic syndrome (MS) in patients with schizophrenia. Exclusion criteria: articles of poor quality. The terminology of the article corresponds to that used in the publications included in the review. The review substantiates the relevance of the problem of MS, discloses the concept and discusses its criteria, provides data on the prevalence of MS in patients with schizophrenia, discusses the relationship between MS and schizophrenia, MS and cognitive impairment in schizophrenia, and describes metabolic changes in patients with a first episode of psychosis or early stage schizophrenia. Recommendations on therapeutic tactics in the development of metabolic syndrome in patients with schizophrenia are given.
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