Related Experiment Video
Updated: Jun 13, 2025

03:54
A New Ex Vivo Model for the Evaluation of Endoscopic Submucosal Injection Material Performance
Published on: October 19, 2018
6.1K
Submucosal injection fluid and tattoo agents.
, Amit Bhatt1, Juan Carlos Bucobo2
1Department of Gastroenterology, Hepatology & Nutrition, Cleveland Clinic, Cleveland, Ohio, USA.
Gastrointestinal Endoscopy
|September 13, 2024
Summary
Endoscopic submucosal dissection and endoscopic mucosal resection use lifting and marking agents to aid lesion removal. Choosing the right agent and technique is crucial for successful endoscopic resection.
Area of Science:
- Gastroenterology
- Endoscopic Surgery
Background:
- Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are minimally invasive endoscopic techniques.
- Submucosal injection aids in lesion identification and creates a cushion for safe resection.
Purpose of the Study:
- To review current techniques and agents for endoscopic marking and lifting of gastrointestinal lesions.
Main Methods:
- MEDLINE database search up to April 2023.
- Keywords included "endoscopy," "marking," "tattoo," and "lifting."
- Report drafted and approved by the American Society for Gastrointestinal Endoscopy Technology Committee.
Main Results:
- Review of techniques for endoscopic tattoo placement and submucosal lifting.
- Description of available agents, their safety, and costs.
Conclusions:
- Endoscopists have various agents for lifting and marking during EMR and ESD.
- Understanding agent properties, techniques, costs, and adverse events is vital for optimal lesion resection.
Related Concept Videos
Drug Delivery: Parenteral Route
445
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
445
Drug Delivery: Miscellaneous Routes
329
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
329
Routes of Drug Administration: Parenteral
1.9K
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
1.9K
Local Anesthetics: Common Agents and Their Applications
416
Local anesthetics (LAs) are commonly used for various applications in medical and dental procedures. Some of the common agents used are cocaine, lidocaine, and bupivacaine.
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
416

