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Updated: Jun 13, 2025

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[Biopsychosocial Factors Influencing Mortality and Functional Recovery in COVID-19 Patients Undergoing Prone

Fabrizio Acevedo P1, José M Aravena C2, Felipe Ceballos V1

  • 1Servicio de Medicina Física y Rehabilitación, Hospital San José, Santiago, Chile.

Revista Medica De Chile
|September 13, 2024
PubMed

Insights

Patients in prone position for COVID-19 requiring ICU care face higher mortality risks. Factors like male sex, older age, and social vulnerability predict mortality, while education and prone positioning cycles aid functional recovery.

Area of Science:

  • Critical Care Medicine
  • Infectious Diseases
  • Public Health

Background:

  • Patients requiring prone positioning for COVID-19 often exhibit more severe disease and complications.
  • Understanding factors influencing outcomes in this vulnerable population is crucial for improving care.

Purpose of the Study:

  • To identify social, health, and hospital factors associated with mortality.
  • To determine factors linked to functional recovery in activities of daily living (ADL) post-ICU discharge.

Main Methods:

  • Prospective observational study conducted from June 2021 to March 2022.
  • Included 85 adult patients admitted to the ICU for COVID-19 requiring prone positioning.
  • Logistic and linear regression analyses were used to assess mortality and functional recovery predictors.

Main Results:

  • Male sex, older age, mental health history, cardiorespiratory disease, and high social priority living were linked to increased in-hospital mortality.
  • Extended hospitalization correlated with poorer functional recovery at discharge and post-discharge.
  • Increased prone positioning cycles and higher education levels were associated with better post-discharge functional recovery.

Conclusions:

  • Biopsychosocial evaluation can predict survival and functional prognosis in severe COVID-19 patients.
  • Intrahospital interventions may enhance short-term functional recovery for critically ill COVID-19 survivors.

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