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Updated: Jun 13, 2025
A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
[Comparison of a portable hemoglobinometer (Verio Q Red) with clinical laboratory results in routine clinical
Boris Trenado-Luengo1, Rosa García-Sierra2, Verónica Moreno Gómez3
1Centre d'Atenció Primària Badalona Bufalà-Canyet, Gerència Territorial Metropolitana Nord, Institut Català de la Salut, Badalona, Barcelona, España; Multidisciplinary Research Group in Health and Society GREMSAS (2021 SGR 01484), Barcelona, España.
Objective:
To analyze the concordance between a hemoglobinometer with capillary blood sample and the clinical laboratory with a venous blood sample.
Design:
Cross-sectional concordance study.
Location:
Care Centre Primary Bufalà-Canyet Primary and Care Centre Primary Dalt la Vila Primary Care Center, Badalona, Barcelona.
Participants:
Random selection of participants who attended routine blood tests. Over 18years old. No abandonment or loss was obtained.
Main Interventions And Measurements:
Sex, age, and reason for the blood test were collected from the medical history. Venous blood is drawn, and simultaneously, capillary blood is collected.
Results:
120 individuals are included, with an average age of 58.9years. The Bland-Almant graph showed differences within the confidence intervals for hemoglobin and hematocrit. The mean differences between the values of the Verio Q Red hemoglobinometer and those of the clinical laboratory were -0.42mg/dl for hemoglobin and -1.25% for hematocrit. The intraclass correlation coefficient showed excellent correlation for hemoglobin and hematocrit between the Verio Q Red hemoglobinometer and the clinical laboratory. Pearson's correlation for hemoglobin was 0.737 and for hematocrit 0.787.
Conclusions:
The Verio Q hemoglobinometer is a valid tool for the early diagnosis of anemias and can be very useful in primary care consultations.
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