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Probiotaceuticals: Back to the future?

Gordon S Howarth1

  • 1School of Animal and Veterinary Sciences, Faculty of Sciences, Engineering and Technology, University of Adelaide, Adelaide, South Australia, Australia; Centre for Paediatric and Adolescent Gastroenterology, North Adelaide, South Australia, Australia.

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|September 13, 2024
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Summary
This summary is machine-generated.

Next-generation probiotics, including pharmabiotics and psychobiotics, offer new therapeutic avenues. Future xenopostbiotics may enhance digestive health, mental well-being, and cancer treatment.

Keywords:
digestive healthnext-generation probioticspharmaceutical probioticsprobiotic metabolite formulationspsychoactive probiotics

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Area of Science:

  • Microbiology
  • Pharmacology
  • Gastroenterology

Background:

  • Probiotic research has evolved beyond simple gut health to explore advanced applications.
  • The search for antibiotic alternatives has driven the development of next-generation probiotics.

Purpose of the Study:

  • To review the evolving landscape of probiotic research, focusing on next-generation probiotics.
  • To highlight the potential of pharmabiotics, psychobiotics, and oncobiotics.

Main Methods:

  • Literature review of recent advancements in probiotic research.
  • Analysis of emerging probiotic categories and their therapeutic potential.

Main Results:

  • Identification of postbiotics, pharmabiotics, psychobiotics, and oncobiotics as key developments.
  • Demonstration of probiotics' potential in mental health and cancer treatment.

Conclusions:

  • Next-generation probiotics, particularly pharmabiotics and psychobiotics, show significant therapeutic promise.
  • Future developments like xenopostbiotics could revolutionize treatment for chronic diseases, including cancer.