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Exploring the Geroprotective Potential of Nutraceuticals

Nadia Alejandra Rivero-Segura1, Emmanuel Alejandro Zepeda-Arzate1, Selma Karime Castillo-Vazquez1,2

  • 1Dirección de Investigación, Instituto Nacional de Geriatría (INGER), Mexico City 10200, Mexico.

Nutrients
|September 14, 2024
PubMed

Insights

Nutraceuticals, natural compounds found in food, show potential as geroprotectors. They may combat cellular damage, reduce age-related diseases, and promote health when consumed regularly or as supplements.

Area of Science:

  • Gerontology and Nutritional Science
  • Molecular Biology of Aging

Background:

  • Aging is characterized by accumulating molecular and cellular damage, increasing the risk of age-related diseases.
  • Geroprotectors are sought to mitigate this damage and prevent age-related conditions.
  • Nutraceuticals, naturally occurring bioactive food compounds, possess health-promoting and disease-preventive properties.

Purpose of the Study:

  • To review the role of nutraceuticals in the aging process.
  • To evaluate nutraceuticals as potential geroprotectors targeting hallmarks of aging.

Main Methods:

  • Systematic literature review of articles published between 2010 and 2023.
  • Data collection from specialized databases: Scopus and PubMed.

Main Results:

  • Nutraceuticals exhibit antioxidant, anti-inflammatory, and antitumoral properties.
  • These properties align with strategies to combat aging hallmarks.
  • Evidence suggests nutraceuticals can play a role in mitigating age-related damage.

Conclusions:

  • Nutraceuticals demonstrate potential as geroprotectors.
  • They can be integrated into the regular diet or used as nutritional supplements to promote healthy aging.
Keywords:
agingbioactive compoundsgeroprotectorshallmarks of agingnutraceuticals

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