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Exploring the Geroprotective Potential of Nutraceuticals
Nadia Alejandra Rivero-Segura1, Emmanuel Alejandro Zepeda-Arzate1, Selma Karime Castillo-Vazquez1,2
1Dirección de Investigación, Instituto Nacional de Geriatría (INGER), Mexico City 10200, Mexico.
Nutrients
|September 14, 2024
Summary
Nutraceuticals, natural compounds found in food, show potential as geroprotectors. They may combat cellular damage, reduce age-related diseases, and promote health when consumed regularly or as supplements.
Area of Science:
- Gerontology and Nutritional Science
- Molecular Biology of Aging
Background:
- Aging is characterized by accumulating molecular and cellular damage, increasing the risk of age-related diseases.
- Geroprotectors are sought to mitigate this damage and prevent age-related conditions.
- Nutraceuticals, naturally occurring bioactive food compounds, possess health-promoting and disease-preventive properties.
Purpose of the Study:
- To review the role of nutraceuticals in the aging process.
- To evaluate nutraceuticals as potential geroprotectors targeting hallmarks of aging.
Main Methods:
- Systematic literature review of articles published between 2010 and 2023.
- Data collection from specialized databases: Scopus and PubMed.
Main Results:
- Nutraceuticals exhibit antioxidant, anti-inflammatory, and antitumoral properties.
- These properties align with strategies to combat aging hallmarks.
- Evidence suggests nutraceuticals can play a role in mitigating age-related damage.
Conclusions:
- Nutraceuticals demonstrate potential as geroprotectors.
- They can be integrated into the regular diet or used as nutritional supplements to promote healthy aging.
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