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CNS prophylaxis in large B-cell lymphomas: A balance with three pans
Teresa Calimeri1, Andrés J M Ferreri1,2
1Lymphoma Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Abstract:
Given the significant limitations of available literature, central nervous system (CNS) prophylaxis in large B-cell lymphomas remains debatable. Wilson and colleagues provide cautious recommendations, on a case-by-case basis, useful to guide discussion with individual patient. In daily practice, CNS relapse risk, prophylaxis safety and prognosis of CNS recurrence must be considered. Commentary on: Wilson et al. Central nervous system prophylaxis in large B-cell lymphoma: A British Society for Haematology Good Practice Paper. Br J Haematol 2024; 205:2198-2205.
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