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New insight on etiology: A chorionic bump with partial mole pregnancy case report from Syria

Ahed Hamed1, Rami Alhouri2, Nour Allahham1

  • 1Department of Obstetrics and Gynecology, Faculty of Medicine, Damascus University, Damascus, Syria.

Journal of Clinical Ultrasound : JCU
|September 14, 2024
PubMed

Keywords:
chorionic bumpdifferential diagnosisetiologyfirst trimesterhydatidiform moleprenatal diagnosisultrasonography

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Nondisjunction01:21

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Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold sister...