Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Bclaf1 drives heart failure by recruiting Srsf2 to enhance Hand2 pre-mRNA splicing and pathological hypertrophy.

Nature communications·2026
Same author

Functional characterization and safety evaluation of an airway commensal <i>Staphylococcus epidermidis</i> HK 95.

Frontiers in microbiology·2026
Same author

Material removal mechanism elucidated by a novel cross-scale model using a unified physical framework linking macroscopic stress distribution and microscopic motion states of abrasives for polishing.

Nanoscale·2026
Same author

Near-complete cryo-EM structure of the Klebsiella pneumoniae podophage RAN69 reveals tail fiber-spike interface and a divergent pre-ejectosome.

Structure (London, England : 1993)·2026
Same author

Development of a Closed One-Tube Colorimetric and Fluorescent LAMP Assay for the Rapid Detection of Feline Herpesvirus 1.

Animals : an open access journal from MDPI·2026
Same author

Viewpoints of community committee workers on public health emergency management in urban communities: a Q methodology study.

Frontiers in public health·2026

Related Experiment Video

Updated: Jun 13, 2025

Doxycycline Loaded Collagen-Chitosan Composite Scaffold for the Accelerated Healing of Diabetic Wounds
10:49

Doxycycline Loaded Collagen-Chitosan Composite Scaffold for the Accelerated Healing of Diabetic Wounds

Published on: August 21, 2021

4.4K

Non-releasing poly (ionic liquid) based hydrogel accelerates diabetic wound healing.

Pan Liu1, Xiaojuan Chen1, Zhiyong Lei1

  • 1Institute of Resource Biology and Biotechnology, Department of Biotechnology, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.

Colloids and Surfaces. B, Biointerfaces
|September 14, 2024
PubMed
Summary

A novel hydrogel made from poly (ionic liquid) and dextran effectively treats diabetic wounds. This advanced wound dressing offers broad-spectrum antibacterial activity and promotes healing without drug resistance.

Keywords:
AntibacterialDiabetic woundHydrogelNon-releasing materialPoly (ionic liquid)

More Related Videos

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
05:18

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

3.7K
Creation and Transplantation of an Adipose-derived Stem Cell ASC Sheet in a Diabetic Wound-healing Model
08:06

Creation and Transplantation of an Adipose-derived Stem Cell ASC Sheet in a Diabetic Wound-healing Model

Published on: August 4, 2017

11.4K

Related Experiment Videos

Last Updated: Jun 13, 2025

Doxycycline Loaded Collagen-Chitosan Composite Scaffold for the Accelerated Healing of Diabetic Wounds
10:49

Doxycycline Loaded Collagen-Chitosan Composite Scaffold for the Accelerated Healing of Diabetic Wounds

Published on: August 21, 2021

4.4K
A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
05:18

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

3.7K
Creation and Transplantation of an Adipose-derived Stem Cell ASC Sheet in a Diabetic Wound-healing Model
08:06

Creation and Transplantation of an Adipose-derived Stem Cell ASC Sheet in a Diabetic Wound-healing Model

Published on: August 4, 2017

11.4K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Wound Healing Research

Background:

  • Diabetic wounds face challenges like bacterial colonization, inflammation, and poor blood vessel formation.
  • Current treatments using bioactive substances can cause drug resistance and tissue damage.

Purpose of the Study:

  • To develop a novel, non-releasing hydrogel for diabetic wound treatment.
  • To address limitations of conventional wound healing strategies.

Main Methods:

  • Synthesized a hydrogel using functional poly (ionic liquid) and modified dextran.
  • Characterized hydrogel properties including adhesion, self-healing, and mechanical strength.
  • Evaluated antibacterial activity, anti-inflammatory effects, and wound healing efficacy in diabetic models.

Main Results:

  • The hydrogel demonstrated excellent tissue adhesion, self-healing, and mechanical properties.
  • Exhibited broad-spectrum antibacterial activity and reduced pro-inflammatory cytokine expression.
  • Significantly enhanced diabetic wound healing compared to the positive control.

Conclusions:

  • The developed hydrogel is a promising alternative to antibiotics for diabetic chronic wounds.
  • Offers a safe and effective approach to wound repair by modulating the wound microenvironment.
  • Highlights the potential of functional poly (ionic liquid) and dextran-based materials in regenerative medicine.