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Updated: Jun 13, 2025

An Acupoint Catgut-embedding Therapy for Treating Obesity
Published on: April 4, 2025
Weight Loss Pharmacotherapy: Current and Future Therapies
Gabriela Jordan1, Sigrid Young1, José O Alemán2
1Department of Medicine, Margaret Corbin Campus of the VA New York Harbor Health Care System, New York, NY, USA; Laboratory of Translational Obesity Research, NYU Langone Health, New York, NY, USA.
Abstract:
The rising prevalence of obesity is of major concern. There are currently 5 Food and Drug Administration-approved medications for the treatment of obesity: orlistat, phentermine/topiramate, naltrexone/bupropion, liraglutide 3.0 mg, and semaglutide 2.4 mg. Surgical options such as bariatric surgery and endoscopic surgery induce more durable weight loss than pharmacotherapy or lifestyle interventions alone. However, patients often experience weight regain and weight loss plateau after surgery. The addition of multimodal or multihormonal pharmacotherapy is a promising tool to address these challenges. The optimal timing of obesity pharmacotherapy with surgical and endoscopic interventions requires further investigation.
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