Anaphylaxis after Treatment with an Endodontic Material Containing Polyethylene Glycol.

Area of Science:

• Dentistry
• Allergology
• Toxicology

Background:

• Polyethylene glycol (PEG) is utilized in endodontic materials to adjust viscosity.
• While generally considered low hazard, parenteral PEG exposure carries an anaphylaxis risk.

Observation:

• Two cases of anaphylaxis occurred following treatment with temporary endodontic filling material containing PEG.
• One patient recovered after hospitalization; the other case was fatal.

Findings:

• Polyethylene glycol (PEG) was identified as the causative agent in these anaphylaxis cases.
• Allergic reactions to PEG are increasingly documented in medical literature.

Implications:

• The findings highlight significant risks associated with PEG in endodontic materials.
• Further investigation and precautionary measures are crucial for patient safety in dental treatments involving PEG.