Related Experiment Video

Updated: Jun 13, 2025

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

304

Preventable vision loss in children with Coats disease

Francisco Altamirano1, Efren Gonzalez1, Ankoor S Shah1

  • 1Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
|September 15, 2024
PubMed

Insights

Amblyogenic refractive error is common in children with Coats disease, affecting 46% of those with available data. Early diagnosis is key to preventing vision loss.

Area of Science:

  • Ophthalmology
  • Pediatric Medicine
  • Genetics

Background:

  • Coats disease is a rare condition affecting retinal blood vessels.
  • Amblyogenic refractive error can lead to permanent vision impairment if not treated.

Purpose of the Study:

  • To determine the prevalence of amblyogenic refractive error in children diagnosed with Coats disease.
  • To identify risk factors associated with amblyogenic refractive error in this pediatric population.

Main Methods:

  • Retrospective chart review of children under 18 with unilateral Coats disease.
  • Data collection included demographics, ocular exams, and treatment history.
  • Analysis focused on prevalence and risk factors for amblyogenic refractive error.

Main Results:

  • Amblyogenic refractive error was identified in 46% of children with available refractive data.
  • Earlier age at diagnosis was associated with a higher likelihood of amblyogenic refractive error.
  • Only 50% of children received glasses, and refractions were not consistently performed.

Conclusions:

  • Amblyogenic refractive error is a significant concern in children with Coats disease.
  • There is a need for better coordination between pediatric and retina specialists.
  • Timely diagnosis and management of refractive errors are crucial for optimal visual outcomes.
Abstract

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