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Updated: Jun 13, 2025
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Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
Published on: April 11, 2025
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Preventable vision loss in children with Coats disease
Francisco Altamirano1, Efren Gonzalez1, Ankoor S Shah1
1Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Summary
Amblyogenic refractive error is common in children with Coats disease, affecting 46% of those with available data. Early diagnosis is key to preventing vision loss.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Genetics
Background:
- Coats disease is a rare condition affecting retinal blood vessels.
- Amblyogenic refractive error can lead to permanent vision impairment if not treated.
Purpose of the Study:
- To determine the prevalence of amblyogenic refractive error in children diagnosed with Coats disease.
- To identify risk factors associated with amblyogenic refractive error in this pediatric population.
Main Methods:
- Retrospective chart review of children under 18 with unilateral Coats disease.
- Data collection included demographics, ocular exams, and treatment history.
- Analysis focused on prevalence and risk factors for amblyogenic refractive error.
Main Results:
- Amblyogenic refractive error was identified in 46% of children with available refractive data.
- Earlier age at diagnosis was associated with a higher likelihood of amblyogenic refractive error.
- Only 50% of children received glasses, and refractions were not consistently performed.
Conclusions:
- Amblyogenic refractive error is a significant concern in children with Coats disease.
- There is a need for better coordination between pediatric and retina specialists.
- Timely diagnosis and management of refractive errors are crucial for optimal visual outcomes.
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