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Anticancer Potential of Pineapple and its Bioactive Compound Bromelain
Davinder Kumar1, Suchitra1, Jyoti Mundlia1
1College of Pharmacy, Pt BD Sharma University of Health Sciences, Rohtak 124001, India.
Current Pharmaceutical Design
|September 16, 2024
Summary
Pineapple and bromelain show promise for cancer treatment, with studies demonstrating benefits in lab and animal models. Further clinical research is needed to confirm efficacy and safety in humans.
Area of Science:
- Oncology
- Pharmacology
- Nutraceuticals
Background:
- Pineapple (Ananas comosus) and its compound bromelain have historical medicinal uses.
- Bromelain is a key bioactive compound in pineapple with recognized health benefits.
Purpose of the Study:
- To review the chemotherapeutic activities of pineapple and bromelain.
- To analyze current literature on their therapeutic potential in cancer treatment.
Main Methods:
- Literature review focusing on existing research.
- Analysis of studies on cell culture and animal disease models.
Main Results:
- Pineapple extract and bromelain show benefits in in vitro and in vivo cancer models.
- Preliminary animal studies indicate potential therapeutic effects.
Conclusions:
- Pineapple and bromelain show promise as anticancer agents.
- Further clinical translation of promising animal model results is necessary.
- These compounds may be well-tolerated, representing a promising research direction.
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