Related Experiment Video
Updated: Jun 13, 2025

05:42
Author Spotlight: Advanced Ex Vivo Model for Investigating Cancer-Adipose Microenvironment Interaction
Published on: January 26, 2024
2.5K
[Obesity and its relationship with cancer]
Ovidio Hernando-Requejo1, Hortensia García de Quinto2
1Servicio de Oncología Radioterápica. Hospital Universitario HM Sanchinarro.
Nutricion Hospitalaria
|September 16, 2024
Summary
Excess weight significantly increases cancer risk, particularly for cancers of the esophagus, stomach, and liver. Maintaining a healthy weight is crucial for cancer prevention and improving patient survival rates.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Background:
- Obesity is a growing global health concern.
- Excess weight is increasingly recognized as a significant risk factor for various non-communicable diseases, including cancer.
Purpose of the Study:
- To investigate the influence of excess weight on cancer risk.
- To identify specific cancer types associated with obesity.
- To explore potential mechanisms linking obesity and cancer.
Main Methods:
- Bibliographic review of studies published between 2000 and 2024.
- Analysis of the relationship between overweight/obesity and cancer incidence.
- Focus on specific cancers sensitive to weight status.
Main Results:
- A significant association between overweight/obesity and elevated cancer risk was confirmed.
- Cancers of the esophagus, stomach, colorectal, liver, and endometrium show particular sensitivity to excess weight.
- Excess weight is a confirmed risk factor for cancer development.
Conclusions:
- Excess weight is a critical modifiable risk factor for cancer development.
- Maintaining a healthy weight is essential for cancer prevention.
- Lifestyle recommendations are vital for cancer prevention and improving outcomes in cancer survivors.
Related Concept Videos
Obesity
411
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
411
Psychoneuroimmunology: Diabetes and Cancer
26
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
26
Cancer Prevention
6.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.1K
Cancer
48.2K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
48.2K
Adaptive Mechanisms in Cancer Cells
5.7K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
5.7K
What is Cancer?
10.6K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
10.6K

