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Updated: Jun 13, 2025

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Delayed systemic arterial-pulmonary arterial shunt simulating pulmonary embolism: An unusual case
Nicholas Puleo1, Nathan Joseph2, Mithra Kimyai-Asadi1
1Department of Diagnostic Radiology, West Virginia University, Morgantown, WV, USA.
Abstract:
This case report describes the imaging findings of an older-aged male presenting with infectious respiratory symptoms. Evaluation with routine contrast-enhanced CT of the chest demonstrated pulmonary artery filling defects initially treated as a pulmonary embolism. However, short-term repeat imaging during pulmonary angiographic and delayed phases demonstrated retrograde filling through a systemic arterial-pulmonary arterial shunt. Given the high prevalence of pulmonary embolism which is also the leading cause of pulmonary angiographic filling defects, this case highlights the importance for clinicians to maintain a differential diagnosis and consider alternative etiologies.
Insights
Imaging revealed pulmonary artery filling defects initially mistaken for pulmonary embolism. Further review showed a systemic arterial-pulmonary arterial shunt, emphasizing the need for differential diagnoses in respiratory cases.
Area of Science:
- Radiology
- Cardiovascular Imaging
- Thoracic Imaging
Background:
- Pulmonary embolism (PE) is a common cause of pulmonary artery filling defects.
- Infectious respiratory symptoms can mimic PE, necessitating careful diagnostic evaluation.
- Systemic arterial-pulmonary arterial shunts are rare but critical differential diagnoses.
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